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STING-ing the antiviral pathway
Free
Peyman Nakhaei
1,2
, John Hiscott
1,2,3
, and Rongtuan Lin
1,3,*
1
Terry Fox Molecular Oncology Group, Lady Davis Institute for Medical Research, Montreal, QC, Canada
2
Department of Microbiology & Immunology, McGill University, Montreal, QC, Canada
3
Department of Medicine, McGill University, Montreal, QC, Canada
*
Correspondence to:Rongtuan Lin, Tel: +514-340-8222; Fax: +514-340-7576; E-mail: rongtuan.lin@mcgill.ca
J Mol Cell Biol
, Volume 2, Issue 3, June 2010, 110-112,
https://doi.org/10.1093/jmcb/mjp048
Abstract
Full Text
The cytosolic DNA sensing pathway has remained poorly defined thus far. A recent study by Ishikawa et al. demonstrates that STING is essential for DNA-mediated type I IFN production and host defence against DNA pathogens.
Volume 2, Issue 3
June 2010
